Relationship between insulin resistance, coronary plaque, and clinical outcomes in patients with acute coronary syndromes: an analysis from the PROSPECT study

We investigated the association of insulin resistance (IR) with coronary plaque morphology and the risk of cardiovascular events in patients enrolled in the Providing Regional Observations to Study Predictors of Events in Coronary Tree (PROSPECT) study. Patients with acute coronary syndromes (ACS) w...

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Veröffentlicht in:Cardiovascular Diabetology 2021-01, Vol.20 (1), p.10-10, Article 10
Hauptverfasser: Farhan, Serdar, Redfors, Björn, Maehara, Akiko, McAndrew, Thomas, Ben-Yehuda, Ori, De Bruyne, Bernard, Mehran, Roxana, Vogel, Birgit, Giustino, Gennaro, Serruys, Patrick W, Mintz, Gary S, Stone, Gregg W
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Sprache:eng
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Zusammenfassung:We investigated the association of insulin resistance (IR) with coronary plaque morphology and the risk of cardiovascular events in patients enrolled in the Providing Regional Observations to Study Predictors of Events in Coronary Tree (PROSPECT) study. Patients with acute coronary syndromes (ACS) were divided based on DM status. Non-DM patients were further stratified according to homeostasis-model-assessment IR (HOMA-IR) index as insulin sensitive (IS; HOMA-IR ≤ 2), likely-IR (LIR; 2 
ISSN:1475-2840
1475-2840
DOI:10.1186/s12933-020-01207-0