Relationship between blood levels of heavy metals and lung function based on the Korean National Health and Nutrition Examination Survey IV-V

Relationship between blood levels of heavy metals and lung function based on the Korean National Health and Nutrition Examination Survey IV-V

Heavy metal exposure may contribute to inflammation in the lungs via increased oxidative stress, resulting in tissue destruction and obstructive lung function (OLF). In this study, we evaluated the relationship between lead and cadmium levels in blood, and lung function in the Korean population. Poo...

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Veröffentlicht in:International journal of chronic obstructive pulmonary disease 2015-01, Vol.10 (Issue 1), p.1559-1570
Hauptverfasser: Leem, Ah Young, Kim, Se Kyu, Chang, Joon, Kang, Young Ae, Kim, Young Sam, Park, Moo Suk, Kim, Song Yee, Kim, Eun Young, Chung, Kyung Soo, Jung, Ji Ye
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Age
Air pollution
Biomarkers - blood
Body mass index
Cadmium
Cadmium - blood
Chi-Square Distribution
Chronic obstructive pulmonary disease
Complications and side effects
Cross-Sectional Studies
Diabetes
Diagnosis
Disease control
Female
Forced Expiratory Volume
Health aspects
Heavy metal poisoning
Heavy metals
Humans
Lead - blood
Linear Models
Logistic Models
Lung - physiopathology
Lung diseases
Lung Diseases, Obstructive - blood
Lung Diseases, Obstructive - diagnosis
Lung Diseases, Obstructive - epidemiology
Lung Diseases, Obstructive - physiopathology
Male
Middle Aged
Multivariate Analysis
Nitrogen dioxide
Nutrition
Nutrition Surveys
Odds Ratio
Original Research
Population
Regression analysis
Republic of Korea - epidemiology
Risk Factors
Smoking
Smoking - adverse effects
Smoking - blood
Spectrophotometry, Atomic
Spirometry
Statistical analysis
Up-Regulation
Vital Capacity
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Zusammenfassung:Heavy metal exposure may contribute to inflammation in the lungs via increased oxidative stress, resulting in tissue destruction and obstructive lung function (OLF). In this study, we evaluated the relationship between lead and cadmium levels in blood, and lung function in the Korean population. Pooled cross-sectional data from 5,972 subjects who participated in the Korean National Health and Nutrition Examination Survey 2008-2012 were used for this study. OLF was defined as forced expiratory volume in 1 second/forced vital capacity (FEV1/FVC)
ISSN:1178-2005
1176-9106
1178-2005
DOI:10.2147/COPD.S86182