Risk factors and predictive markers of post-stroke cognitive decline-A mini review

Stroke is one of the top causes of death and disability worldwide. Cognitive impairments are found in more than 70% of individuals who have survived a stroke. Cognitive decline is a major contributor to disability, dependency, and morbidity. The prevalence and severity of dementia vary depending on...

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Veröffentlicht in:	Frontiers in aging neuroscience 2024-02, Vol.16, p.1359792-1359792
Hauptverfasser:	Guo, Xiaofan, Phan, Cattien, Batarseh, Sanad, Wei, Miao, Dye, Justin
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of daily living acute stroke intervention Age ageing Biomarkers Blood flow Cerebral blood flow cerebrovascular disease Cognition & reasoning Cognitive ability cognitive decline Dementia Dementia disorders Executive function Gender differences Hemorrhage Ischemia Memory Morbidity Mortality Neuroscience Quality of life Reperfusion Risk factors Stroke Women
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Zusammenfassung:	Stroke is one of the top causes of death and disability worldwide. Cognitive impairments are found in more than 70% of individuals who have survived a stroke. Cognitive decline is a major contributor to disability, dependency, and morbidity. The prevalence and severity of dementia vary depending on different characteristics of the stroke and other clinical risk factors. Here we discuss the effects of stroke territory, patients' age, sex, cerebral blood flow, acute reperfusion therapy, and cognitive reserve of post-stroke cognitive decline. Potential predictive molecular and genetic biomarkers of post-stroke cognitive impairments are also discussed.
ISSN:	1663-4365 1663-4365
DOI:	10.3389/fnagi.2024.1359792