Tracheobronchial adenoid cystic carcinoma treated with radical radiochemotherapy: Case report and review of literature

Adenoid cystic carcinoma (ACC) is a low-grade malignancy of the elderly but has shown aggressive behavior. It is most commonly found in minor salivary glands and rarely in lacrimal glands, tracheobronchial tree, lung parenchyma, breast, cervix, skin, esophagus, prostate. The standard of care of ACC is essentially surgery followed by post-operative adjuvant radiation therapy depending upon various adverse features. Here we report an unusual tracheo-bronchial ACC in a 32-year-old lady who was treated with radical radiotherapy under image guidance along with concurrent chemotherapy using intravenous cisplatin on weekly basis. Response evaluation with 18FDG PET-CECT three months after the completion of treatment showed complete response, and has also remained disease free clinically at 3 years follow-up, without any late radiation toxicity.