Effects of glycyrrhetinic acid β on growth and virulence of Aeromonas hydrophila

is a significant pathogen to freshwater farmed animals, and antibiotics are usually used to control the bacterial septicemia caused by . Due to the severe situation of development and spread of antibiotic resistance, there are stricter restrictions on antibiotics used in aquaculture. To evaluate the feasibility of glycyrrhetinic acid β (GA) as an alternative therapy against bacterial infection, in this study, an isolated from diseased fish is used to test the antibacterial, anti-virulence activity and therapeutic effect of GA and , respectively. Results showed that GA did not affect the growth of , while it could down-regulate (