Effect of astaxanthin- and tocotrienol-containing foods on the ocular function of healthy individuals: A randomized, placebo-controlled, double-blind, parallel-group trial

[Display omitted] •Astaxanthin + tocotrienol improved post-VDT visual acuity in patients aged ≥40 years.•The combination therapy significantly mitigated VA reduction after VDT work.•Patients had better functional VA after 6-week astaxanthin + tocotrienol intake.•Astaxanthin + tocotrienol improved av...

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Veröffentlicht in:Journal of functional foods 2024-11, Vol.122, p.106456, Article 106456
Hauptverfasser: Sekikawa, Takahiro, Kizawa, Yuki, Li, Yanmei, Miura, Naoki
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Sprache:eng
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Zusammenfassung:[Display omitted] •Astaxanthin + tocotrienol improved post-VDT visual acuity in patients aged ≥40 years.•The combination therapy significantly mitigated VA reduction after VDT work.•Patients had better functional VA after 6-week astaxanthin + tocotrienol intake.•Astaxanthin + tocotrienol improved average functional VA post-VDT compared to placebo. We examined a 6-week consumption effect of astaxanthin- and tocotrienol-containing foods on ocular function pre- and post-visual display terminal (VDT) work in a randomized, placebo-controlled, parallel-group study including 60 healthy adults. For 6 weeks, participants consumed astaxanthin (9 mg/day) + tocotrienol (50 mg/day)- or placebo-containing foods. The astaxanthin + tocotrienol group had significantly better corrected post-VDT visual acuity (VA) in the dominant eye than the placebo group according to the measured value and change from pre-VDT after 6 weeks of astaxanthin + tocotrienol consumption (p 
ISSN:1756-4646
DOI:10.1016/j.jff.2024.106456