Marine sponge derived natural products between 2001 and 2010: trends and opportunities for discovery of bioactives

Marine sponges belonging to the phylum Porifera (Metazoa), evolutionarily the oldest animals are the single best source of marine natural products. The present review presents a comprehensive overview of the source, taxonomy, country of origin or geographical position, chemical class, and biological...

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Veröffentlicht in:	Marine drugs 2014-08, Vol.12 (8), p.4539-4577
Hauptverfasser:	Mehbub, Mohammad Ferdous, Lei, Jie, Franco, Christopher, Zhang, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals anticancer bioactive compounds Biological Factors - chemistry Biological Factors - pharmacology Biological Products - chemistry Biological Products - pharmacology drug Marine Marine Biology - methods marine natural products marine sponges Metazoa Porifera Porifera - chemistry Review sponge-associated bacteria
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Beschreibung
Zusammenfassung:	Marine sponges belonging to the phylum Porifera (Metazoa), evolutionarily the oldest animals are the single best source of marine natural products. The present review presents a comprehensive overview of the source, taxonomy, country of origin or geographical position, chemical class, and biological activity of sponge-derived new natural products discovered between 2001 and 2010. The data has been analyzed with a view to gaining an outlook on the future trends and opportunities in the search for new compounds and their sources from marine sponges.
ISSN:	1660-3397 1660-3397
DOI:	10.3390/md12084539