A facile, solvent and catalyst free, microwave assisted one pot synthesis of hydrazinyl thiazole derivatives

A facile, solvent and catalyst free, microwave assisted one pot synthesis of hydrazinyl thiazole derivatives

A rapid synthesis of hydrazinyl thiazoles under solvent and catalyst free condition is reported within 30 s. A series of aryl ketones/4-benzoyl pyridine thiosemicarbazone, thiosemicarbazide and α-haloketones were used. This is an environmentally benign microwave assisted and efficient method for rap...

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Veröffentlicht in:Journal of Saudi Chemical Society 2015-03, Vol.19 (2), p.200-206
Hauptverfasser: Chinnaraja, D., Rajalakshmi, R.
Format: Artikel
Sprache:eng
Schlagworte:
Acetaminophen
Aryl ketones
Caffeine
Cyclocondenzation
Green synthesis
Hydrazinyl thiazoles
α-Haloketones
الأسيتامينوفين
الشاي
القهوة
الكافيين
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Zusammenfassung:A rapid synthesis of hydrazinyl thiazoles under solvent and catalyst free condition is reported within 30 s. A series of aryl ketones/4-benzoyl pyridine thiosemicarbazone, thiosemicarbazide and α-haloketones were used. This is an environmentally benign microwave assisted and efficient method for rapid synthesis of hydrazinyl thiazoles.
ISSN:1319-6103
DOI:10.1016/j.jscs.2014.05.001