Allamanda cathartica : A Review of the Phytochemistry, Pharmacology, Toxicology, and Biotechnology

In this work, we explore the current knowledge about the phytochemistry and in vitro and in vivo evaluations of the extracts and, where appropriate, the main active components characterized and isolated from the . Of the 15 species, most phytochemical, pharmacological, and toxicological studies have focused on . These plants are used for the treatment of various health disorders. Numerous phytochemical investigations of plants from the have shown the presence of hydrocarbons, alcohols, esters, ethers, aldehydes, ketones, fatty acids, phospholipids, volatile compounds, phenolic compounds, flavonoids, alkaloids, steroids, terpenes, lactones, and carbohydrates. Various studies have confirmed that extracts and active substances isolated from the have multiple pharmacological activities. The species has emerged as a source of traditional medicine used for human health. Further studies on the phytochemical, pharmacological, and toxicological properties and their mechanisms of action, safety, and efficacy in the species of is recommended.