$Overweight and obesity impair left ventricular systolic function as measured by left ventricular ejection fraction and global longitudinal strain$

Overweight and obesity impair left ventricular systolic function as measured by left ventricular ejection fraction and global longitudinal strain

Obesity is associated with type 2 diabetes mellitus, left ventricular diastolic dysfunction and heart failure but it is unclear to which extent it is related to left ventricular systolic dysfunction. The aim of the study was to explore the effects of overweight and obesity on left ventricular systol...

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Veröffentlicht in:	Cardiovascular Diabetology 2018-08, Vol.17 (1), p.113-113, Article 113
Hauptverfasser:	Blomstrand, Peter, Sjöblom, Peter, Nilsson, Mats, Wijkman, Magnus, Engvall, Martin, Länne, Toste, Nyström, Fredrik H, Östgren, Carl Johan, Engvall, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analysis Biomechanical Phenomena Body mass Body Mass Index Body weight Cardiac output Cardiovascular disease Case-Control Studies Complications and side effects Coronary vessels Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - physiopathology Echocardiography Echocardiography, Doppler Ejection fraction Family medical history Female Health aspects Heart attack Heart diseases Heart failure Humans Hypertension Left ventricular function Male Middle Aged Myocardial Contraction Obesity Obesity - complications Obesity - diagnosis Obesity - physiopathology Original Investigation Overweight Patients Population Prognosis Prospective Studies Regression analysis Risk Factors Stroke Volume Time Factors Ultrasonic imaging Ventricle Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - etiology Ventricular Dysfunction, Left - physiopathology Ventricular Function, Left
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Zusammenfassung:	Obesity is associated with type 2 diabetes mellitus, left ventricular diastolic dysfunction and heart failure but it is unclear to which extent it is related to left ventricular systolic dysfunction. The aim of the study was to explore the effects of overweight and obesity on left ventricular systolic function in patients with type 2 diabetes mellitus and a control group of non-diabetic persons. We prospectively investigated 384 patients with type 2 diabetes mellitus, and 184 controls who participated in the CARDIPP and CAREFUL studies. The participants were grouped according to body mass index (normal weight
ISSN:	1475-2840 1475-2840
DOI:	10.1186/s12933-018-0756-2