Combined prognostic value of malnutrition using GLIM criteria and renal insufficiency in elderly heart failure

Aims We aimed to investigate the prognostic impact of malnutrition, defined by the Global Leadership Initiative on Malnutrition (GLIM) criteria, stratified by renal function in hospitalized patients with acute decompensated heart failure (HF). Methods and results In this retrospective study, 314 patients who were hospitalized for acute decompensated HF from August 2019 to October 2020 were enrolled. We evaluated malnutrition using the GLIM criteria during the time of admission. The primary outcome was 90‐day all‐cause mortality. The median patient age was 82 years, and 90‐day mortality was 14.0%. In total, 76 (24.2%) patients were malnourished according to the GLIM criteria. Malnutrition defined by the GLIM criteria [adjusted hazard ratio (HR) 1.41, 95% confidence interval (CI) 1.02–1.91, P = 0.036] and renal insufficiency [adjusted HR 2.59, 95% CI 1.07–6.28, P = 0.035 for estimated glomerular filtration rate (eGFR)