Unravelling the role of key genes in oral cancer progression: A comprehensive review
•In worldwide, 90% of oral cancer are caused by oral squamous cell carcinoma (OSCC), also common seen in the Indian subcontinent.•Genetic mutations in key genes such as EGFR, HER2 and TP53 are important in the development of oral cancer.•Critical screening and identification of molecular biomarkers...
Gespeichert in:
| Veröffentlicht in: | Oral oncology reports 2024-06, Vol.10, p.100384, Article 100384 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | •In worldwide, 90% of oral cancer are caused by oral squamous cell carcinoma (OSCC), also common seen in the Indian subcontinent.•Genetic mutations in key genes such as EGFR, HER2 and TP53 are important in the development of oral cancer.•Critical screening and identification of molecular biomarkers are essential to developing new treatment and diagnostic approaches.•Oncogenes and tumor suppressor genes play a significant role in the spread of oral cancer indicating the significance of targeted genetic therapy. |
|---|---|
| ISSN: | 2772-9060 2772-9060 |
| DOI: | 10.1016/j.oor.2024.100384 |