TOTAL CHOLESTEROL / HIGH DENSITY LIPOPROTEIN CHOLESTEROL RATIO, TRIGLYCERIDES / HIGH DENSITY LIPOPROTEIN CHOLESTEROL WITH THE CONTROLLED ATTENUATION PARAMETER (CAP) IN NON-ALCOHOLIC FATTY LIVER

Non-Alcoholic Fatty Liver Disease (NAFLD) is a global public health problem. The ratio of Total Cholesterol (TC) to High Density Lipoprotein Cholesterol (HDL) and Ultrasensitive C-Reactive Protein have been a biomarker of cardiovascular risk. In a study of the Chinese population, the CT/HDL ratio wa...

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Veröffentlicht in:Annals of hepatology 2022-01, Vol.27, p.100643, Article 100643
Hauptverfasser: Barrientos, C.N. Ascencio, Lupitou, L.C. Barrios, Orellana, R.M. Rivera, Flores, A.G. Rivera, Mejía Loza, M.I.S.
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Sprache:eng
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Zusammenfassung:Non-Alcoholic Fatty Liver Disease (NAFLD) is a global public health problem. The ratio of Total Cholesterol (TC) to High Density Lipoprotein Cholesterol (HDL) and Ultrasensitive C-Reactive Protein have been a biomarker of cardiovascular risk. In a study of the Chinese population, the CT/HDL ratio was established as a predictor of metabolic syndrome and NAFLD >3.8 The optimal cut-off level to predict NAFLD according to the ratio triglycerides (TG)/HDL was established in women >0.9 and in men > 1.4, with sensitivity and specificity of 78 and 77.3% respectively. There are optimal cut-off values of CT/HDL and TG/HDL to predict NAFLD4. However, they have not been associated with the degree of hepatic fat infiltration using Transient Elastography (FibroScan®) study by CAP, with a sensitivity of 82% and specificity of 91%. Objective: To describe the relationship CT/HDL, TG/HDL with the controlled attenuation parameter in patients diagnosed with non-alcoholic fatty liver. Retrospective study in patients registered in the database of the Gastroenterology outpatient clinic of the Juárez Hospital in Mexico, with a diagnosis of NAFLD, from January 1, 2017 to April 30, 2019, who underwent Fibroscan. The data were obtained from the records of the outpatient clinic and clinical record, it was analyzed in the statistical program Jamovi 1.1.9, to obtain means, medians and percentages. Chi-square test was used for analysis of categorical variables and unidirectional analysis of variance (ANOVA) for continuous variables, establishing a p
ISSN:1665-2681
2659-5982
DOI:10.1016/j.aohep.2021.100643