Risk factors for anthroponotic cutaneous leishmaniasis in unresponsive and responsive patients in a major focus, southeast of Iran

Cutaneous leishmaniasis (CL) is a serious health challenge at the global level due to Leishmania tropica. This study was conducted to evaluate the risk factors associated with anthroponotic CL (ACL) in unresponsive (patient who does not heal and remains with an active lesion, despite receiving two c...

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Veröffentlicht in:PloS one 2018-02, Vol.13 (2), p.e0192236
Hauptverfasser: Bamorovat, Mehdi, Sharifi, Iraj, Aflatoonian, Mohammad Reza, Sharifi, Hamid, Karamoozian, Ali, Sharifi, Fatemeh, Khosravi, Ahmad, Hassanzadeh, Saeid
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Sprache:eng
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Zusammenfassung:Cutaneous leishmaniasis (CL) is a serious health challenge at the global level due to Leishmania tropica. This study was conducted to evaluate the risk factors associated with anthroponotic CL (ACL) in unresponsive (patient who does not heal and remains with an active lesion, despite receiving two courses of intra-lesional Glucantime along with cryotherapy and one cycle of systemic Glucantime) and responsive patients in a major focus in southeastern Iran. A case-control study was conducted from April 2015 to October 2016 in the southeast of Iran. Patients were recruited in a major ACL focus from unresponsive and responsive cases. These patients were compared for environmental, clinical, and demographic characteristic factors. Twenty-five risk related factors were analyzed using multivariate logistic regression and backward elimination stepwise models. P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0192236