Malnutrition outweighs the effect of the obesity paradox

Malnutrition outweighs the effect of the obesity paradox

Background High body mass index (BMI) is paradoxically associated with better outcome in patients with heart failure (HF). The effects of malnutrition on this phenomenon across the whole spectrum of HF have not yet been studied. Methods In this observational study, patients were classified by guidel...

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Veröffentlicht in:Journal of cachexia, sarcopenia and muscle sarcopenia and muscle, 2022-06, Vol.13 (3), p.1477-1486
Hauptverfasser: Prausmüller, Suriya, Heitzinger, Gregor, Pavo, Noemi, Spinka, Georg, Goliasch, Georg, Arfsten, Henrike, Gabler, Cornelia, Strunk, Guido, Hengstenberg, Christian, Hülsmann, Martin, Bartko, Philipp E.
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Algorithms
Body mass index
Cardiac arrhythmia
Cardiovascular disease
Coronary vessels
Diabetes
Ejection fraction
Female
Heart failure
Heart Failure - classification
Heart Failure - complications
Heart Failure - diagnosis
Heart Failure - epidemiology
Humans
Hypertension
Laboratories
Lymphocytes
Male
Malnutrition
Malnutrition - complications
Malnutrition - epidemiology
Medical prognosis
Middle Aged
Nutritional Status
Obesity
Obesity - complications
Obesity - epidemiology
Obesity paradox
Original
Patients
PNI
Prognosis
Pulmonary arteries
Statistical analysis
Stroke Volume
Vein & artery diseases
Weight control
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Zusammenfassung:Background High body mass index (BMI) is paradoxically associated with better outcome in patients with heart failure (HF). The effects of malnutrition on this phenomenon across the whole spectrum of HF have not yet been studied. Methods In this observational study, patients were classified by guideline diagnostic criteria to one of three heart failure subtypes: reduced (HFrEF), mildy reduced (HFmrEF), and preserved ejection fraction (HFpEF). Data were retrieved from the Viennese‐community healthcare provider network between 2010 and 2020. The relationship between BMI, nutritional status reflected by the prognostic nutritional index (PNI), and survival was assessed. Patients were classified by the presence (PNI 
ISSN:2190-5991
2190-6009
DOI:10.1002/jcsm.12980