Measures of postprandial lipoproteins are not associated with coronary artery disease in patients with type 2 diabetes mellitus1

Measures of postprandial lipoproteins are not associated with coronary artery disease in patients with type 2 diabetes mellitus1

Individuals with type 2 diabetes mellitus (DM) characteristically have elevated fasting and postprandial (PP) plasma triglycerides (TG). Previous case-control studies indicated that PPTG levels predict the presence of coronary artery disease (CAD) in people without DM; however, the data for patients...

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Veröffentlicht in:Journal of lipid research 2009-09, Vol.50 (9), p.1901-1909
Hauptverfasser: Reyes-Soffer, Gissette, Holleran, Steve, Karmally, Wahida, Ngai, Colleen I., Chen, Niem-Tzu, Torres, Margarita, Ramakrishnan, Rajasekhar, Blaner, William S., Berglund, Lars, Ginsberg, Henry N., Tuck, Catherine
Format: Artikel
Sprache:eng
Schlagworte:
apolipoprotein B48
remnant lipoproteins
triglycerides
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Zusammenfassung:Individuals with type 2 diabetes mellitus (DM) characteristically have elevated fasting and postprandial (PP) plasma triglycerides (TG). Previous case-control studies indicated that PPTG levels predict the presence of coronary artery disease (CAD) in people without DM; however, the data for patients with DM are conflicting. Therefore, we conducted a case-control study in DM individuals, 84 with (+) and 80 without (−) CAD. Our hypothesis was that DM individuals with or without CAD would have similar PPTG levels, but CAD+ individuals would have more small d
ISSN:0022-2275
1539-7262
DOI:10.1194/jlr.M900092-JLR200