Application of Haematological Indices in the Diagnosis of Swine Influenza Infection in Adults

Introduction: The differential diagnoses of patients hospitalised for Influenza-Like Illness (ILI) due to swine influenza virus vs other pathogens are challenging. Aim: To evaluate haematological indices such as lymphocyte (LYM), platelet (PLT), Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and Lymphocyte multiplied by Platelet Count (LYM×PLT) as potential indicators to discriminate swine influenza virus infection from another ILI in Adults. Materials and Methods: This study was conducted among 332 patients, admitted with ILI from January 2019 to December 2019. Complete Blood Count (CBC) and Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) to detect swine influenza virus from throat/nasal swab were performed in each patient. Based on results, patients were divided into swine influenza-positive and swine influenza-negative groups. ANOVA test was used to compare different groups. The diagnostic values of the haematological indices in swine influenza infection were evaluated, using the ROC curve. p-value