COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report

SARS‐CoV‐2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID‐19 illness. Aggressive anti‐COVID‐19 therapy with a high‐dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and...

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Veröffentlicht in:Clinical case reports 2022-12, Vol.10 (12), p.e6790-n/a
Hauptverfasser: Bunch, Connor M., Zackariya, Nuha, Thomas, Anthony V., Langford, Jack H., Aboukhaled, Michael, Thomas, Samuel J., Ansari, Aida, Patel, Shivani S., Buckner, Hallie, Miller, Joseph B., Annis, Christy L., Quate‐Operacz, Margaret A., Schmitz, Leslie A., Pulvirenti, Joseph J., Konopinski, Jonathan C., Kelley, Kathleen M., Hassna, Samer, Nelligan, Luke G., Walsh, Mark M.
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Sprache:eng
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Zusammenfassung:SARS‐CoV‐2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID‐19 illness. Aggressive anti‐COVID‐19 therapy with a high‐dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and complement activation on the endothelial surface in response to acute infection. COVID‐associated rashes in adults usually associate with more severe COVID‐19 illness. For older, comorbid patients with mild to moderate COVID‐19 illness who develop a rash, administer early immunomodulating therapy to mitigate disease progression.
ISSN:2050-0904
2050-0904
DOI:10.1002/ccr3.6790