Antigenic Characterization of Novel Human Norovirus GII.4 Variants San Francisco 2017 and Hong Kong 2019

Norovirus is a major cause of acute gastroenteritis; GII.4 is the predominant strain in humans. Recently, 2 new GII.4 variants, Hong Kong 2019 and San Francisco 2017, were reported. Characterization using GII.4 monoclonal antibodies and serum demonstrated different antigenic profiles for the new var...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Emerging infectious diseases 2024-05, Vol.30 (5), p.1026-1029
Hauptverfasser:	Tohma, Kentaro, Landivar, Michael, Ford-Siltz, Lauren A, Pilewski, Kelsey A, Kendra, Joseph A, Niendorf, Sandra, Parra, Gabriel I
Format:	Artikel
Sprache:	eng
Schlagworte:	acute gastroenteritis Antibodies, Monoclonal - immunology Antibodies, Viral - blood Antibodies, Viral - immunology Antigenic Characterization of Novel Human Norovirus GII.4 Variants San Francisco 2017 and Hong Kong 2019 Antigens, Viral - genetics Antigens, Viral - immunology Caliciviridae Infections - epidemiology Caliciviridae Infections - immunology Caliciviridae Infections - virology Causes of Dispatch Distribution Gastroenteritis Gastroenteritis - epidemiology Gastroenteritis - virology Gene mutations Genetic aspects Genotype GII.4 variants Hong Kong - epidemiology Hong Kong 2019 variant Humans Identification and classification Monoclonal antibodies Mutation Norovirus Norovirus - classification Norovirus - genetics Norovirus - immunology Pandemics Phylogeny San Francisco - epidemiology San Francisco 2017 variant Viral antigens Viral proteins Virus research Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Norovirus is a major cause of acute gastroenteritis; GII.4 is the predominant strain in humans. Recently, 2 new GII.4 variants, Hong Kong 2019 and San Francisco 2017, were reported. Characterization using GII.4 monoclonal antibodies and serum demonstrated different antigenic profiles for the new variants compared with historical variants.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid3005.231694