Correlation of Systemic Immune Inflammatory Index and Systemic Inflammatory Response Index with Microalbuminuria in Middle-aged and Elderly People Undergoing Health Examination

Background Microalbuminuria is a sensitive indicator of early renal microvascular damage and an independent risk factor for cardiovascular diseases. Previous studies have shown that long-term chronic inflammation plays an important role in the occurrence and development of microalbuminuria. However, the correlation between blood inflammatory markers and microalbuminuria has been less frequently reported. Objective To investigate the correlation of systemic immune inflammatory index (SII) and systemic inflammatory response index (SIRI) with microalbuminuria in a middle-aged and elderly physical examination population. Methods This was a cross-sectional study in which 2 105 medical examiners over the age of 40 years who underwent health check-ups from April to July 2023 at the Department of Health Medicine, General Hospital of the Eastern Theatre of Operations were selected as study subjects. The study subjects were divided into two groups based on the urinary microalbumin/urinary creatinine ratio (UACR) values