Urinary bladder melanosis with complete resolution case report

Background Melanosis of the bladder is a rare condition characterized by multifocal, diffuse melanin pigmentation of the urothelial mucosa or lamina propria without any proliferation of melanocytes. Less than 25 cases have been reported so far of which only four patients had concurrent urothelial carcinoma. Case presentation We are reporting a case of melanosis of the bladder in a 58-year-old female associated with pTaG1 transitional urothelial cell carcinoma (TCC) of the bladder who presented with symptoms of recurrent urinary tract infection (UTI). Cystoscopy and biopsy results confirmed benign melanosis. Conclusion Our case is unique because bladder melanosis associated low grade TCC with complete resolution of both conditions within one year.