CLINICAL AND PATHOLOGOANATOMIC CHARACTERISTICS OF ADVERSE OUTCOMES OF SARS-COV-2 IN A LEVEL III HOSPITAL

Aim. Clinical and pathological analysis of adverse outcomes of SARS-CoV-2 in a repurposed level III infectious diseases hospital. Materials and methods: The analysis of case histories and the results of postmortem examination of deceased SARS-CoV-2 patients hospitalized in a re-profiled infectious diseases hospital, created on the basis of a level III hospital, in the period 06.12.2020 to 11.12.2020 was carried out. Statistical analysis was carried out using the Statsoft Statistica 6.0 software. Absolute values were described by the median (Me) and interquartile range, relative values – by percentage. Results. The mortality rate for SARS-CoV-2 in a repurposed infectious diseases hospital over a five-month period was 11.9 %. Pathological examination of the deaths from SARS-CoV-2 revealed pneumonia in 82.4 % (72.1 % bilateral), hydrothorax in 47.4 %, pulmonary edema in 94.8 %, myocardial infarction in 88.6 %, PE in 5.1 %, sepsis in 32.9 %. The causes of death of patients with COVID-19 were: pulmonary heart failure – 65.9 %, multiple organ failure – 29.8 %, edema and dislocation of the brain – 17.5 %, PE – 5.1 %. Conclusion. Mortality in a re-profiled infectious diseases hospital on the basis of a level III hospital was comparable in value to other similar institutions. In patients who died from COVID-19, the following adverse factors prevailed: old age, female sex, polymorbid pathology.