Effects of tranexamic acid on vascular occlusive events and perioperative resuscitation in patients with atrial fibrillation undergoing total joint arthroplasty

Effects of tranexamic acid on vascular occlusive events and perioperative resuscitation in patients with atrial fibrillation undergoing total joint arthroplasty

The Institutional Review Board of West China Hospital of Sichuan University approved this study (No. 2012268). Parameters Non-TXA group (n = 216) TXA group (n = 246) P value Preoperative oral anticoagulation 0.680  Warfarin 54 48  Aspirin 36 39  Clopidogrel 33 30  B-receptor blocker 90 87 0.165 Accu...

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Veröffentlicht in:Chinese medical journal 2022-10, Vol.135 (19), p.2354-2356
Hauptverfasser: Tang, Shangkun, Zhou, Zongke, Yang, Jing, Kang, Pengde, Shen, Bin, Pei, Fuxing, Shi, Xiaojun
Format: Artikel
Sprache:eng
Schlagworte:
Anticoagulants
Antifibrinolytic Agents
Arthroplasty
Arthroplasty, Replacement, Hip
Atrial Fibrillation
Blood Loss, Surgical
Bone surgery
Cardiac arrhythmia
Correspondence
Drug dosages
Embolisms
Hemoglobin
Hospitals
Humans
Joint replacement surgery
Mortality
Orthopedics
Patients
Stroke
Thrombosis
Tranexamic Acid
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Zusammenfassung:The Institutional Review Board of West China Hospital of Sichuan University approved this study (No. 2012268). Parameters Non-TXA group (n = 216) TXA group (n = 246) P value Preoperative oral anticoagulation 0.680  Warfarin 54 48  Aspirin 36 39  Clopidogrel 33 30  B-receptor blocker 90 87 0.165 Accumulated vascular occlusive event  Postoperative 30 days 6 3 0.227  Postoperative 90 days 15 12 0.345 Total blood loss (mL) 1149.6 ± 556.6 748.5 ± 338.4
ISSN:0366-6999
2542-5641
DOI:10.1097/CM9.0000000000002114