Novel parvovirus and related variant in human plasma

We report a novel parvovirus (PARV4) and related variants in pooled human plasma used in the manufacture of plasma-derived medical products. Viral DNA was detected by using highly selective polymerase chain reaction assays; 5% of pools tested positive, and amounts of DNA ranged from 106 copies/mL pl...

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Veröffentlicht in:	Emerging infectious diseases 2006-01, Vol.12 (1), p.151-154
Hauptverfasser:	Fryer, Jacqueline F, Kapoor, Amit, Minor, Philip D, Delwart, Eric, Baylis, Sally A
Format:	Artikel
Sprache:	eng
Schlagworte:	Care and treatment Diagnosis Dispatch DNA, Viral - analysis DNA, Viral - genetics Humans Parvoviridae Infections - blood Parvoviridae Infections - virology Parvovirus Parvovirus - genetics Parvovirus - isolation & purification Parvovirus infections Phylogeny plasma Plasma - virology Risk factors United Kingdom
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Beschreibung
Zusammenfassung:	We report a novel parvovirus (PARV4) and related variants in pooled human plasma used in the manufacture of plasma-derived medical products. Viral DNA was detected by using highly selective polymerase chain reaction assays; 5% of pools tested positive, and amounts of DNA ranged from 106 copies/mL plasma.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid1201.050916