Ethyl 2-hydroxy-2-phenyl-2-(thiazol-2-yl)acetate

Ethyl 2-hydroxy-2-phenyl-2-(thiazol-2-yl)acetate

This short note describes the synthesis of the title compound through spontaneous aerobic oxidation of ethyl 2-phenyl-2-(thiazol-2-yl)acetate. Due to the prevalence of such functional motifs in biologically active substances, we believe the oxidation encountered highlights an important degradation p...

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Veröffentlicht in:MolBank 2015-05, Vol.2015 (2), p.M857
Hauptverfasser: Mallia, Carl, Englert, Lukas, Walter, Gary, Baxendale, Ian
Format: Artikel
Sprache:eng
Schlagworte:
heterocycles
oxidation product
thiazole
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Zusammenfassung:This short note describes the synthesis of the title compound through spontaneous aerobic oxidation of ethyl 2-phenyl-2-(thiazol-2-yl)acetate. Due to the prevalence of such functional motifs in biologically active substances, we believe the oxidation encountered highlights an important degradation pathway worthy of note.
ISSN:1422-8599
1422-8599
DOI:10.3390/M857