Bedside spleen stiffness measurement can be reliably performed in most cases: High applicability and reproducibility using a specific 100‐Hz module on vibration‐controlled transient elastography

Given the well-known limitations of liver stiffness measurement (LSM),[ 1] spleen stiffness measurement (SSM) using the standard liver 50-Hz module on vibration controlled transient elastography (FibroScan; Echosens) was first proposed by Stefanescu et al. in 2011[ 2] as a potential additional noninvasive tool (NIT) to assess the presence/absence of high-risk varices. Since the first publication, several other authors have tested SSM, showing that it correlates hepatic venous pressure gradient (HVPG) with the size of esophageal varices and with liver-related events in patients with compensated advanced chronic liver disease (cACLD). [...]importantly, SSM using the standard 50-Hz liver module fails in 10%–27% of cases and is almost invariably not applicable to normal size spleens. [...]in this population, a SSM@100 Hz for the XL probe would be a useful development.