Genetic Characterization of Japanese Encephalitis Virus Genotype 5 Isolated from Patient, South Korea, 2015

We isolated Japanese encephalitis virus genotype 5 from human specimens in South Korea. Whole-genome analysis showed 90.4% identity with other genotype 5 viruses from humans. This virus had a unique insertion in the NS4A gene. However, the envelope protein contained Lys 84, which was specific to str...

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Veröffentlicht in:	Emerging infectious diseases 2020-05, Vol.26 (5), p.1002-1006
Hauptverfasser:	Woo, Jae Hoon, Jeong, Young Eui, Jo, Jung Eun, Shim, Sang-Mu, Ryou, Jungsang, Kim, Kyung-Chang, Lee, Won Ja, Lee, Joo-Yeon
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Analysis Characterization Disease control Disease prevention Dispatch Encephalitis Epidemiology Genes Genetic aspects genetic characterization Genetic Characterization of Japanese Encephalitis Virus Genotype 5 Isolated from Patient, South Korea, 2015 Genomes Genomics Genotype & phenotype genotype 5 Identity Japanese encephalitis Japanese encephalitis virus Mosquitoes Patients Phylogenetics Proteins RNA South Korea Vaccines Viruses West Nile virus
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Zusammenfassung:	We isolated Japanese encephalitis virus genotype 5 from human specimens in South Korea. Whole-genome analysis showed 90.4% identity with other genotype 5 viruses from humans. This virus had a unique insertion in the NS4A gene. However, the envelope protein contained Lys 84, which was specific to strains of genotype 5 viruses from South Korea.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2605.190977