Quantitative and Sensitive Detection of Chloramphenicol by Surface-Enhanced Raman Scattering

Quantitative and Sensitive Detection of Chloramphenicol by Surface-Enhanced Raman Scattering

We used surface-enhanced Raman scattering (SERS) for the quantitative and sensitive detection of chloramphenicol (CAP). Using 30 nm colloidal Au nanoparticles (NPs), a low detection limit for CAP of 10 M was obtained. The characteristic Raman peak of CAP centered at 1344 cm was used for the rapid qu...

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Veröffentlicht in:Sensors (Basel, Switzerland) Switzerland), 2017-12, Vol.17 (12), p.2962
Hauptverfasser: Ding, Yufeng, Zhang, Xin, Yin, Hongjun, Meng, Qingyun, Zhao, Yongmei, Liu, Luo, Wu, Zhenglong, Xu, Haijun
Format: Artikel
Sprache:eng
Schlagworte:
Antibiotics
Au nanoparticles
chloramphenicol
Chloromycetin
Gold
High performance liquid chromatography
Nanoparticles
quantitative detection
Raman spectra
surface-enhanced Raman scattering
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Zusammenfassung:We used surface-enhanced Raman scattering (SERS) for the quantitative and sensitive detection of chloramphenicol (CAP). Using 30 nm colloidal Au nanoparticles (NPs), a low detection limit for CAP of 10 M was obtained. The characteristic Raman peak of CAP centered at 1344 cm was used for the rapid quantitative detection of CAP in three different types of CAP eye drops, and the accuracy of the measurement result was verified by high-performance liquid chromatography (HPLC). The experimental results reveal that the SERS technique based on colloidal Au NPs is accurate and sensitive, and can be used for the rapid detection of various antibiotics.
ISSN:1424-8220
1424-8220
DOI:10.3390/s17122962