4-Chloro-2-((1 R )-1-{[( R )-(2-chlorophenyl)(cyclopentyl)methyl]amino}ethyl)phenol
The title compound, C20H23Cl2NO, was prepared by condensation of (R)-1-(2-chlorophenyl)-1-cyclopentylmethanamine with 1-(5-chloro-2-hydroxyphenyl)ethanone, resulting in the formation of a new chiral center. The structural analysis confirms the absolute configuration of the title compound and the for...
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Veröffentlicht in: | Acta crystallographica. Section E, Structure reports online Structure reports online, 2008-11, Vol.64 (11), p.o2211-o2212 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | The title compound, C20H23Cl2NO, was prepared by condensation of (R)-1-(2-chlorophenyl)-1-cyclopentylmethanamine with 1-(5-chloro-2-hydroxyphenyl)ethanone, resulting in the formation of a new chiral center. The structural analysis confirms the absolute configuration of the title compound and the formation of the (R,R) diastereoisomer. There is an intramolecular O-H...N hydrogen bond which stabilizes the conformation of the molecule. The molecules are linked to each other through weak C-H...π interactions. |
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ISSN: | 1600-5368 1600-5368 |
DOI: | 10.1107/S1600536808034624 |