Concomitant diagnosis of Trypanosoma cruzi and HIV in a patient with neurologic manifestations: A case report

American trypanosomiasis or Chagas disease is a vector-borne infection caused by the protozoan parasite Trypanosoma cruzi, characterized by acute and chronic phases; reactivations due to immunosuppression can occur. In this case report, we confirm the presence of trypomastigotes of T. cruzi in a pat...

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Veröffentlicht in:The Brazilian journal of infectious diseases 2024-11, Vol.28 (6), p.104478, Article 104478
Hauptverfasser: Molina Solano, Emmanuel, Mora Díaz, Mauricio, Montoya Madriz, Stephanie, Lizano Calvo, Mauricio, Retana Moreira, Lissette
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Sprache:eng
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Zusammenfassung:American trypanosomiasis or Chagas disease is a vector-borne infection caused by the protozoan parasite Trypanosoma cruzi, characterized by acute and chronic phases; reactivations due to immunosuppression can occur. In this case report, we confirm the presence of trypomastigotes of T. cruzi in a patient with neurologic manifestations. For this purpose, a battery of techniques, including direct examination of cerebrospinal fluid, Giemsa stains, sample cultures, serology and molecular techniques were employed. The patient was treated with nifurtimox for 6 months and started antiretroviral therapy as the concomitant diagnosis of HIV was also performed, showing no sequelae nor adverse effects. A follow-up of the patient´s health status was performed for 42 months.
ISSN:1413-8670
1678-4391
1678-4391
DOI:10.1016/j.bjid.2024.104478