The Association between Plasma miRNA-21 Levels with Overall 1-year Survival Rate of Breast Cancer Patients at Various Stages

The Association between Plasma miRNA-21 Levels with Overall 1-year Survival Rate of Breast Cancer Patients at Various Stages

Background: miRNA 21 exhibits an increased expression in breast cancer (BC). However, its relationship with the 1-year survival of breast cancer patients is still disputable and under serious discussion. Methods: Cohort prospective study involving 49 breast cancer patients was done, comprising 26 in...

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Veröffentlicht in:Acta medica Indonesiana 2022-01, Vol.53 (4)
Hauptverfasser: Pradana Zaky Romadhon, Ami Ashariati Prayoga, Siprianus Ugroseno Yudho Bintoro, Muhammad Noor Diansyah, Putu Niken Amrita, Merlyna Savitri, Choirina Windradi
Format: Artikel
Sprache:eng
Schlagworte:
breast cancer
health
mirna-21
mortality rate
survival
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Zusammenfassung:Background: miRNA 21 exhibits an increased expression in breast cancer (BC). However, its relationship with the 1-year survival of breast cancer patients is still disputable and under serious discussion. Methods: Cohort prospective study involving 49 breast cancer patients was done, comprising 26 in early stage and 23 in end-stage. We evaluated miRNA-21 values and observed its association with mortality within 1 year. Results: In general, there was a correlation between the increase in miRNA-21 levels and the mortality rate of breast cancer patients (r = 0.651; p
ISSN:0125-9326
2338-2732