Structures and Biological Activities of Secondary Metabolites from Trichoderma harzianum

Structures and Biological Activities of Secondary Metabolites from Trichoderma harzianum

The biocontrol fungus Trichoderma harzianum, from both marine and terrestrial environments, has attracted considerable attention. T. harzianum has a tremendous potential to produce a variety of bioactive secondary metabolites (SMs), which are an important source of new herbicides and antibiotics. Th...

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Veröffentlicht in:Marine drugs 2022-11, Vol.20 (11), p.701
Hauptverfasser: Guo, Rui, Li, Gang, Zhang, Zhao, Peng, Xiaoping
Format: Artikel
Sprache:eng
Schlagworte:
Acids
Antibiotics
bioactivity
Biological control
Cancer
Cytotoxicity
Fungi
Herbicides
HIV
Human immunodeficiency virus
Kinases
Leukemia
Marine biology
marine sources
Metabolites
Natural products
Polyketides
Review
Secondary metabolites
Terpenes
Terrestrial environments
Trichoderma harzianum
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Zusammenfassung:The biocontrol fungus Trichoderma harzianum, from both marine and terrestrial environments, has attracted considerable attention. T. harzianum has a tremendous potential to produce a variety of bioactive secondary metabolites (SMs), which are an important source of new herbicides and antibiotics. This review prioritizes the SMs of T. harzianum from 1988 to June 2022, and their relevant biological activities. Marine-derived SMs, especially terpenoids, polyketides, and macrolides compounds, occupy a significant proportion of natural products from T. harzianum, deserving more of our attention.
ISSN:1660-3397
1660-3397
DOI:10.3390/md20110701