Tympanoplasty: A Comparative Cross-sectional Study to Assess the Predictors of Surgical Success at a Tertiary Care Setting in Karachi

Objective: To determine the factors that could affect the success of tympanoplasty and the surgical outcomesat a tertiary care hospital in Karachi.Study Design: Comparative cross-sectional study design.Place and Duration of Study: The study was carried out at the Department of ENT, Head and Neck Surgery, Dow University of Health Sciences, Dr. K.M Ruth Pfau Civil Hospital Karachi, Pakistan from January 2021 to January 2022.Methods: Fifty-two patients with chronic otitis media without cholesteatoma (COMNC) who hadtympanoplasty (underlay, inlay with graft) were included in this study. The examiner assessed the patients byassessment protocol that included patients who presented signs and symptoms with NCCOM with detailedhistory taking, a targeted physical exam (Rhinoscopy and otoscopy), nasofibroscopy, an audiogram, and videodocumentation via video-otoscopy to better visualize the tympanic membrane perforation. Descriptivestatistics were applied to all parameters. The parameters under investigation were compared by using the chisquare test, and the Whitney U test or the Wilcoxon Rank Sum Test statistical were used for stratificationconsidering P-value ≤ 0.05 as significant.Results: Tympanic membrane perforations were significantly affected by factors such as age, location, and sizeof the perforation, number of ear infections per year, family history of hearing loss and otorrhea, history, thestatus of tympanic cavity, graft type, Surgery success rate, the graft, technique, or access used. The closuresuccess rate was 73.1%.Conclusion: Our study concluded that the factors that interfere with tympanic membrane restoration werestatistically significant. After the initial surgery, the closure success rate was 73.1% with audiometric Gain.