DNA Extraction Systematics for Spectroscopic Studies

Study of genetic material allows the comprehension the origin of the many biochemical changes that follow diseases, like cancer, promoting the development of early preventive inquiry and more efficient individual treatments. Raman spectroscopy can be an important tool in DNA study, since it allows p...

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Veröffentlicht in:Sensors (Basel, Switzerland) Switzerland), 2008-06, Vol.8 (6), p.3624-3632
Hauptverfasser: Palma, Bianca Fogazza, Ferrari, Amanda Borges, Bitar, Renata Andrade, Cardoso, Maria Angélica Gargione, Martin, Airton A, Da Silva Martinho, Herculano
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Sprache:eng
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Zusammenfassung:Study of genetic material allows the comprehension the origin of the many biochemical changes that follow diseases, like cancer, promoting the development of early preventive inquiry and more efficient individual treatments. Raman spectroscopy can be an important tool in DNA study, since it allows probe molecular vibrations of genetic material in a fast way. The present work established a systematic way for extract DNA in suitable concentrations and structural integrity allowing studies by Raman spectroscopy or other spectroscopic technique, including bio-analytical sensors for probing genetic alterations.
ISSN:1424-8220
1424-8220
DOI:10.3390/s8063624