Carbapenem-Resistant Klebsiella pneumoniae Isolated From a Patient in a Midwestern U.S. Hospital With a History of Indian Travel: Therapeutic Strategies and Clinical Outcomes

Carbapenem-Resistant Klebsiella pneumoniae Isolated From a Patient in a Midwestern U.S. Hospital With a History of Indian Travel: Therapeutic Strategies and Clinical Outcomes

Carbapenemases have had increasing prevalence within the United States and worldwide. Here, we present a case of carbapenem-resistant (CRKP) which is unique due to the rarity of multiple mechanisms of resistance within the harboring New Delhi metallo- -lactamases (NDM), oxacillinase-48 (OXA-48)-like...

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Veröffentlicht in:Case reports in infectious diseases 2025-01, Vol.2025 (1), p.8155592
Hauptverfasser: Phan, Christopher, Tsai, Kristen, Gill, Christian M, Chamberland, Robin, Hendrix, Christian, Hou, Rong
Format: Artikel
Sprache:eng
Schlagworte:
Abdomen
Antibiotics
Antimicrobial agents
Bacterial pneumonia
Beta lactamases
Care and treatment
Case Report
Disease prevention
E coli
Enzymes
Hepatitis
Imipenem
Infections
Intubation
Laboratories
Neutropenia
Oxalic acid
Patient outcomes
Pneumonia
Posaconazole
Type 2 diabetes
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Zusammenfassung:Carbapenemases have had increasing prevalence within the United States and worldwide. Here, we present a case of carbapenem-resistant (CRKP) which is unique due to the rarity of multiple mechanisms of resistance within the harboring New Delhi metallo- -lactamases (NDM), oxacillinase-48 (OXA-48)-like, and cefotaximase (CTX-M) resistance genes, detected in a patient following an international travel. This case demonstrates the need for a multidisciplinary approach to optimize the treatment of multidrug-resistant Gram-negative organisms.
ISSN:2090-6625
2090-6633
DOI:10.1155/crdi/8155592