Complete and de novo assembly of the Leishmania braziliensis (M2904) genome

Leishmania braziliensis is the etiological agent of American mucosal leishmaniasis, one of the most severe clinical forms of leishmaniasis. Here, we report the assembly of the L. braziliensis (M2904) genome into 35 continuous chromosomes. Also, the annotation of 8395 genes is provided. The public av...

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Veröffentlicht in:	Memórias do Instituto Oswaldo Cruz 2019-01, Vol.114, p.e180438-e180438
Hauptverfasser:	González-de la Fuente, Sandra, Camacho, Esther, Peiró-Pastor, Ramón, Rastrojo, Alberto, Carrasco-Ramiro, Fernando, Aguado, Begoña, Requena, Jose M
Format:	Artikel
Sprache:	eng
Schlagworte:	chromosomes DNA, Protozoan - genetics gene annotation genome assembly Illumina short reads Leishmania braziliensis - genetics next generation sequencing PacBio long reads PARASITOLOGY Sequence Analysis, DNA Short Communication TROPICAL MEDICINE
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Beschreibung
Zusammenfassung:	Leishmania braziliensis is the etiological agent of American mucosal leishmaniasis, one of the most severe clinical forms of leishmaniasis. Here, we report the assembly of the L. braziliensis (M2904) genome into 35 continuous chromosomes. Also, the annotation of 8395 genes is provided. The public availability of this information will contribute to a better knowledge of this pathogen and help in the search for vaccines and novel drug targets aimed to control the disease caused by this Leishmania species.
ISSN:	0074-0276 1678-8060 1678-8060
DOI:	10.1590/0074-02760180438