Is low total cholesterol levels associated with suicide attempt in depressive patients?

Is low total cholesterol levels associated with suicide attempt in depressive patients?

Patients with major depressive disorder (MDD) have a high risk of suicide. Many pathophysiological factors involved in MDD and suicide such us a low cholesterol levels have been associated with MDD and increased vulnerability to suicide. In this study, we investigate the relation between lipid param...

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Veröffentlicht in:Annals of general psychiatry 2017-04, Vol.16 (1), p.20-20, Article 20
Hauptverfasser: Messaoud, A, Mensi, R, Mrad, A, Mhalla, A, Azizi, I, Amemou, B, Trabelsi, I, Grissa, M H, Salem, N Haj, Chadly, A, Douki, W, Najjar, M F, Gaha, L
Format: Artikel
Sprache:eng
Schlagworte:
Biological marker
Cholesterol
Depression
Depression, Mental
Health aspects
High density lipoprotein
Lipids
Low density lipoprotein
Measurement
Mental depression
Physiological aspects
Plasma levels
Primary Research
Risk factors
Self destructive behavior
Suicidal behavior
Suicide
Suicides & suicide attempts
Triglycerides
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Zusammenfassung:Patients with major depressive disorder (MDD) have a high risk of suicide. Many pathophysiological factors involved in MDD and suicide such us a low cholesterol levels have been associated with MDD and increased vulnerability to suicide. In this study, we investigate the relation between lipid parameters and suicide risk in patients with MDD. Plasma levels of total cholesterol, triglycerides, and high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c) were determined in 160 patients meeting the DSM-IV-TR criteria for MDD (110 patients without suicidal behavior and 52 suicidal attempters) and 151 healthy controls. A significant decrease in plasma cholesterol levels was observed in the group of suicidal depressive patients compared to those without suicidal behavior (  
ISSN:1744-859X
1744-859X
DOI:10.1186/s12991-017-0144-4