Acanthosis nigricans and insulin resistance in obese children

Acanthosis nigricans and insulin resistance in obese children

Background Acanthosis nigricans (AN) is a skin condition characterized by darkening and thickening of skin. AN has been reported to be linked to insulin resistance (IR), that associated with type 2 diabetes, in obese children in many country.Objective To determine the relation between acanthosis nig...

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Veröffentlicht in:Paediatrica Indonesiana 2010-10, Vol.50 (5), p.274-7
Hauptverfasser: Tirtamulia, Kristellina Sangirta, Umboh, Adrian, Warouw, Sarah Maria, Pateda, Vivekenanda, Regina, Frecillia
Format: Artikel
Sprache:eng
Schlagworte:
acanthosis nigricans
insulin resistance
obese
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Zusammenfassung:Background Acanthosis nigricans (AN) is a skin condition characterized by darkening and thickening of skin. AN has been reported to be linked to insulin resistance (IR), that associated with type 2 diabetes, in obese children in many country.Objective To determine the relation between acanthosis nigricans and insulin resistance in obese children.Methods We conducted a cross sectional study in Wenang District, Manado, from October 2009 until January 2010. We examined 54 obese children aged 10-14  years for insulin resistance using Homeostasis Model Assessment of Insulin Resistance Index (HOMA-IR). We analyzed the results byT-test and phi coefficient correlation. The value of P
ISSN:0030-9311
2338-476X
DOI:10.14238/pi50.5.2010.274-7