Paradoxical reactions and immune reconstitution inflammatory syndrome in tuberculosis
Highlights • Case definitions for paradoxical reactions and immune reconstitution inflammatory syndrome (IRIS) in tuberculosis (TB) are reviewed. • The risk factors and immunopathogenesis of these conditions are explored. • Pathogenesis is discussed in the context of recent advances in TB research....
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Veröffentlicht in: | International journal of infectious diseases 2015-03, Vol.32 (C), p.39-45 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Highlights • Case definitions for paradoxical reactions and immune reconstitution inflammatory syndrome (IRIS) in tuberculosis (TB) are reviewed. • The risk factors and immunopathogenesis of these conditions are explored. • Pathogenesis is discussed in the context of recent advances in TB research. • A hypothesis is proposed for their core underlying pathogenesis. |
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ISSN: | 1201-9712 1878-3511 |
DOI: | 10.1016/j.ijid.2014.12.030 |