Chikungunya fever outbreak, Bhutan, 2012

In 2012, chikungunya virus (CHIKV) was reported for the first time in Bhutan. IgM ELISA results were positive for 36/210 patient samples; PCR was positive for 32/81. Phylogenetic analyses confirmed that Bhutan CHIKV belongs to the East/Central/South African genotype. Appropriate responses to future...

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Veröffentlicht in:	Emerging infectious diseases 2013-10, Vol.19 (10), p.1681-1684
Hauptverfasser:	Wangchuk, Sonam, Chinnawirotpisan, Piyawan, Dorji, Tshering, Tobgay, Tashi, Dorji, Tandin, Yoon, In-Kyu, Fernandez, Stefan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Alphavirus Alphavirus Infections - blood Alphavirus Infections - epidemiology Alphavirus Infections - immunology Amino Acid Sequence Antibodies, Viral - blood Bhutan Bhutan - epidemiology Chikungunya Fever Chikungunya virus Chikungunya virus - genetics Chikungunya virus - immunology Chikungunya virus - isolation & purification Child Child, Preschool Disease Outbreaks Dispatch Enzyme-linked immunosorbent assay Female Health aspects Humans Immunoglobulin M - blood Immunoglobulins Infant Male Middle Aged Molecular Diagnostic Techniques Molecular Sequence Data outbreak Phylogeny Reverse Transcriptase Polymerase Chain Reaction Togaviridae Vaccines Viral Envelope Proteins - genetics Young Adult
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Beschreibung
Zusammenfassung:	In 2012, chikungunya virus (CHIKV) was reported for the first time in Bhutan. IgM ELISA results were positive for 36/210 patient samples; PCR was positive for 32/81. Phylogenetic analyses confirmed that Bhutan CHIKV belongs to the East/Central/South African genotype. Appropriate responses to future outbreaks require a system of surveillance and improved laboratory capacity.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid1910.130453