Determination of Oxidative Stress Related Toxicity on Repeated Dermal Exposure of Hydroxyapatite Nanoparticles in Rats

Determination of Oxidative Stress Related Toxicity on Repeated Dermal Exposure of Hydroxyapatite Nanoparticles in Rats

Hydroxyapatite nanoparticles (HANPs) have numerous applications, such as substitute for bone grafting, bone fillers, bioceramic coating, and dental fillings. The toxicity of these nanomaterials is of growing concern despite their significant scientific interest and promising potential in many applic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:International Journal of Biomaterials 2014-01, Vol.2014 (2014), p.88-95
Hauptverfasser: Mohanan, P. V., Arumugam, Sabareeswaran, Santhakumar, Syama
Format: Artikel
Sprache:eng
Schlagworte:
Antioxidants
Biocompatibility
Biomedical materials
Bones
Chemical reactions
Drug delivery systems
Enzymes
Hydroxyapatite
Liver
Nanomaterials
Nanoparticles
Nanotechnology
Observations
Organs
Oxidative stress
Rats
Rodents
Surgical implants
Toxicity
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Hydroxyapatite nanoparticles (HANPs) have numerous applications, such as substitute for bone grafting, bone fillers, bioceramic coating, and dental fillings. The toxicity of these nanomaterials is of growing concern despite their significant scientific interest and promising potential in many applications. In this study, an in-house synthesized, characterized HANP of size
ISSN:1687-8787
1687-8795
DOI:10.1155/2014/476942