Nanoscale Drug Delivery Systems in Glioblastoma

Glioblastoma is the most aggressive cerebral tumor in adults. However, the current pharmaceuticals in GBM treatment are mainly restricted to few chemotherapeutic drugs and have limited efficacy. Therefore, various nanoscale biomaterials that possess distinct structure and unique property were constr...

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Veröffentlicht in:Nanoscale research letters 2022-02, Vol.17 (1), p.27-27, Article 27
Hauptverfasser: Liu, Zihao, Ji, Xiaoshuai, He, Dong, Zhang, Rui, Liu, Qian, Xin, Tao
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Sprache:eng
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Zusammenfassung:Glioblastoma is the most aggressive cerebral tumor in adults. However, the current pharmaceuticals in GBM treatment are mainly restricted to few chemotherapeutic drugs and have limited efficacy. Therefore, various nanoscale biomaterials that possess distinct structure and unique property were constructed as vehicles to precisely deliver molecules with potential therapeutic effect. In this review, nanoparticle drug delivery systems including CNTs, GBNs, C-dots, MOFs, Liposomes, MSNs, GNPs, PMs, Dendrimers and Nanogel were exemplified. The advantages and disadvantages of these nanoparticles in GBM treatment were illustrated.
ISSN:1931-7573
1556-276X
1556-276X
DOI:10.1186/s11671-022-03668-6