How does obesity lead to insulin resistance?

How does obesity lead to insulin resistance?

Experiments on mice show that an enzyme called DNA methyltransferase 3a is involved in insulin resistance via an epigenetic mechanism.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:eLife 2017-12, Vol.6
Hauptverfasser: Choi, Chan Hee J, Cohen, Paul
Format: Artikel
Sprache:eng
Schlagworte:
adipocyte
Adipocytes
Cell Biology
Deoxyribonucleic acid
Diabetes
DNA
DNA methylation
DNA methyltransferase
Enzymes
epigenetic
Epigenetics
Gene expression
Glucose
Insight
Insulin
Insulin resistance
Laboratories
Obesity
type 2 diabetes
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Experiments on mice show that an enzyme called DNA methyltransferase 3a is involved in insulin resistance via an epigenetic mechanism.
ISSN:2050-084X
2050-084X
DOI:10.7554/eLife.33298