Spontaneous Brain Activities in Hyperthyroidism Patients Assessed Using Fractional Amplitude of Low-frequency Fluctuation

Background Hyperthyroidism is a common endocrine psychosomatic disease, which is often accompanied by negative emotions, seriously affecting the prognosis of patients. Moreover, it is associated with more than 5 times more higher risk of committing suicide. Therefore, it has certain clinical and soc...

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Veröffentlicht in:Zhongguo quanke yixue 2022-11, Vol.25 (33), p.4173-4178
1. Verfasser: WU Xiaoran, WANG Xiaoyue, GENG Yibo, ZHANG Hongxing, ZHANG Haisan
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Sprache:chi
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Zusammenfassung:Background Hyperthyroidism is a common endocrine psychosomatic disease, which is often accompanied by negative emotions, seriously affecting the prognosis of patients. Moreover, it is associated with more than 5 times more higher risk of committing suicide. Therefore, it has certain clinical and social significance to explore the neuroimaging characteristics of brain damage in patients with hyperthyroidism. Objective To analyze the abnormal patterns of spontaneous brain activity measured by resting-state functional magnetic resonance imaging (rs-fMRI) , and the neuroimaging characteristics of brain damage in patients with hyperthyroidism. Methods Participants were recruited from December 2014 to June 2016, including 25 hyperthyroidism outpatients with 131I therapy from Xinxiang Central Hospital, and 28 sex-, age-, and education level-matched healthy volunteers from the same hospital and the community near the hospital. Symptom Checklist-90 (SCL-90) was used to assess the mental health. rs-fMRI was performed t
ISSN:1007-9572
DOI:10.12114/j.issn.1007-9572.2022.0498