Fixation artefact in an intra-operative frozen section: a potential cause of misinterpretation

The intra-operative histological assessment of fresh tissue can provide valuable diagnostic information and guide surgical management, however, even a limited exposure to standard fixation agents can potentially compromise analysis. Defined handling strategies should exist to facilitate the receipt...

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Veröffentlicht in:	Journal of cardiothoracic surgery 2007-10, Vol.2 (1), p.45-45, Article 45
Hauptverfasser:	Thomson, Andrew M, Wallace, William A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged, 80 and over Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - surgery Diagnostic Errors - prevention & control Fixatives Frozen Sections - methods Humans Intraoperative Care - methods Letters to the Editor Lung Neoplasms - diagnosis Lung Neoplasms - surgery Male Specimen Handling - adverse effects
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Beschreibung
Zusammenfassung:	The intra-operative histological assessment of fresh tissue can provide valuable diagnostic information and guide surgical management, however, even a limited exposure to standard fixation agents can potentially compromise analysis. Defined handling strategies should exist to facilitate the receipt of all specimens, in their optimal state, by the laboratory.
ISSN:	1749-8090 1749-8090
DOI:	10.1186/1749-8090-2-45