IgG glomerulonephritis: a morphologic study of a rare entity

Mesangial IgG glomerulonephritis (MesIgGN) is recently recognized as a distinct type of glomerulonephritis. In our renal biopsy series, two patients with MesIgGN were identified. The morphologic criteria detected in these patients included mesangial dense deposits by ultrastructural studies, which were predominantly positive for IgG by immunofluorescence. Both patients were young boys, one presented with hematuria and the other with the nephrotic syndrome. Similar cases have been reported in other studies from around the world; however, this is the first report of MesIgGN from Saudi Arabia.