Fluphenazine dihydrochloride dimethanol solvate

In the title compound {systematic name: 1-(2-hydroxyethyl)-4-[3-(2-trifluoromethyl-10 H -phenothiazin-10-yl)propyl]piperazine-1,4-diium dichloride dimethanol disolvate}, C 22 H 28 F 3 N 3 OS 2+ ·2Cl − ·2CH 3 OH, the dihedral angle between the planes of the two outer benzene rings of the tricyclic ph...

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Veröffentlicht in:Acta crystallographica. Section E, Structure reports online Structure reports online, 2012-04, Vol.68 (4), p.o1004-o1005
Hauptverfasser: Petrus, Joanna, Petrus, Rafał, Czarnik-Matusewicz, Bogusława
Format: Artikel
Sprache:eng
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Zusammenfassung:In the title compound {systematic name: 1-(2-hydroxyethyl)-4-[3-(2-trifluoromethyl-10 H -phenothiazin-10-yl)propyl]piperazine-1,4-diium dichloride dimethanol disolvate}, C 22 H 28 F 3 N 3 OS 2+ ·2Cl − ·2CH 3 OH, the dihedral angle between the planes of the two outer benzene rings of the tricyclic phenothiazine system is 46.91 (13)°. The piperazine ring adopts a chair conformation. The crystal structure is stabilized by O—H...Cl, N—H...Cl, C—H...O, C—H...Cl and C—H...F hydrogen bonds and contacts.
ISSN:1600-5368
1600-5368
DOI:10.1107/S1600536812008707