Motor symptom machine rating system for complete MDS-UPDRS III in Parkinson's disease: A proof-of-concept pilot study

The study was approved by Ruijin Hospital Ethics Committee, Shanghai Jiao Tong University School of Medicine (No. 2015-99). MDS-UPDRS III ITEM ACCAbsolute ACCAcceptable ICC (95% CIs, Level) MDS-UPDRS III ITEM ACCAbsolute ACCAcceptable ICC (95% CIs, Level) 3.1 Speech 0.93 / 0.93* (0.90–0.95, Excellent) 3.10 Gait 0.88 0.90 0.80* (0.74–0.85, Excellent) 3.2 Facial Expression 0.71 0.71 0.63* (0.52–0.72, Good) 3.11 Freezing of Gait 0.94 0.96 0.74* (0.65–0.81, Excellent) 3.3a Rigidity-Neck 0.85 / 0.76* (0.68–0.83, Excellent) 3.12 Postural Stability 0.87 0.85 0.87* (0.82–0.90, Excellent) 3.3b Rigidity-UE 0.73 / 0.62* (0.54–0.69, Good) 3.13 Posture 0.70 0.74 0.54* (0.42–0.65, Fair) 3.3c Rigidity-LE 0.71 / 0.78* (0.73–0.82, Excellent) 3.14 Global Spontaneity of Movement 0.91 0.91 0.83* (0.77–0.88, Excellent) 3.4 Finger Tapping 0.73 0.71 0.78* (0.73–0.82, Excellent) 3.15 Postural Tremor 0.81 0.86 0.60* (0.51–0.67, Good) 3.5 Hand Movements 0.70 0.75 0.69* (0.62–0.74, Good) 3.16 Kinetic Tremor 0.79 0.85 0.51* (0.39–0.60, Fair) 3.6 Pronation-Supination Movements of Hands 0.76 0.80 0.73* (0.68–0.78, Good) 3.17a Rest Tremor Amplitude Lip/Jaw 0.88 0.89 0.41* (0.29–0.52, Fair) 3.7 Toe Tapping 0.78 0.80 0.79* (0.75–0.83, Excellent) 3.17b Rest Tremor Amplitude UE 0.91 0.91 0.38* (0.27–0.47, Poor) 3.8 Leg Agility 0.70 0.82 0.78* (0.73–0.82, Excellent) 3.17c Rest Tremor Amplitude LE 0.98 0.97 0.80* (0.73–0.85, Excellent) 3.9 Arising from Chair 0.75 0.82 0.28* (0.13–0.43, Poor) 3.18 Constancy of Rest Tremor 0.84 0.86 0.72* (0.63–0.79, Good) *P