Opportunistic double vital staining screening can lead to early oral squamous cell carcinoma diagnosis

•Oral cancer is a global health concern, having significant morbidity and mortality owing to delays in diagnosis.•Early detection of oral potentially malignant disorders and oral cancer can help improve the survival rates and quality of life.•Opportunistic oral cancer screening using simple, easy-to-use, patient-friendly, cost-effective, and accurate tool is required.•Double staining procedure using Methylene Blue and Lugol's Iodine can be tried in mass oral cancer screening programs.