A people-centered decentralized outreach model toward HCV micro-elimination in hyperendemic areas: COMPACT study in SARS Co–V2 pandemic

Gaps in linkage-to-care remain the barriers toward hepatitis C virus (HCV) elimination in the directly-acting-antivirals (DAA) era, especially during SARS Co–V2 pandemics. We established an outreach project to target HCV micro-elimination in HCV-hyperendemic villages. The COMPACT provided “door-by-d...

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Veröffentlicht in:	Journal of microbiology, immunology and infection immunology and infection, 2023-06, Vol.56 (3), p.586-597
Hauptverfasser:	Huang, Ching-I, Liang, Po-Cheng, Wei, Yu-Ju, Tsai, Pei-Chien, Hsu, Po-Yao, Hsieh, Ming-Yen, Liu, Ta-Wei, Lin, Yi-Hung, Hsieh, Meng-Hsuan, Jang, Tyng-Yuan, Wang, Chih-Wen, Yang, Jeng-Fu, Yeh, Ming-Lun, Huang, Chung-Feng, Dai, Chia-Yen, Chuang, Wan-Long, Huang, Jee-Fu, Yu, Ming-Lung
Format:	Artikel
Sprache:	eng
Schlagworte:	COMPACT DAA HCV Hepacivirus Hepatitis C Hyperendemic areas Microelimination Original Pandemic SARS Co–V2
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Zusammenfassung:	Gaps in linkage-to-care remain the barriers toward hepatitis C virus (HCV) elimination in the directly-acting-antivirals (DAA) era, especially during SARS Co–V2 pandemics. We established an outreach project to target HCV micro-elimination in HCV-hyperendemic villages. The COMPACT provided “door-by-door” screening by an “outreach HCV-checkpoint team” and an “outreach HCV-care team” for HCV diagnosis, assessment and DAA therapy in Chidong/Chikan villages between 2019 and 2021. Participants from neighboring villages served as Control group. A total of 5731 adult residents participated in the project. Anti-HCV prevalence rate was 24.0% (886/3684) in Target Group and 9.5% (194/2047) in Control group (P
ISSN:	1684-1182 1995-9133
DOI:	10.1016/j.jmii.2023.04.012